Search results for "PPARa GENE VARIATION"

PPARa GENE VARIATION AND PHISYCAL PERFORMANCE IN ITALIAN SOCCER PLAYERS

2012

PURPOSE: One of the genes of the health-related fitness phenotype is a PPARα coding for peroxisome proliferator activator receptor alpha, a central regulator of expression of genes involved in fatty acid metabolism. The aim of our research was to study the role of polymorphism of PPARα gene in performance enhancing in Italian soccer players. METHODS: Sixty professional soccer players and thirty sedentary volunteers were enrolled in the study. Samples of venous blood were obtained at rest in the morning by conventional clinical procedures. Serum was collected and lipid profile was measured by using a commercial kit. An aliquote of anticoagulant-treated blood was used to prepare genomic DNA f…